Xiaomin Bao Assistant Professor

Research Summary:

The Bao lab uses human skin as a model system to study the epigenomic regulation of progenitor maintenance and tissue differentiation. We are interested in how chromatin architecture and modifications dictate gene expression in a genome­wide scale.

Selected Publications:

A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63. Bao X, Rubin AJ, Qu K, Zhang J, Giresi PG, Chang HY, and Khavari PA. Genome Biology. 2015 December 18;16(1):284.

ACTL6a Enforces the Epidermal Progenitor State by Suppressing SWI/SNF-Dependent Induction of KLF4. Bao X, Tang J, Lopez-Pajares V, Tao S, Qu K, Crabtree GR, and Khavari PA. Cell Stem Cell. 2013 February 7;12(2):193-203.

The COOH-terminal Domain of the JIL-1 Histone H3S10 Kinase Interacts with Histone H3 and Is Required for Correct Targeting to Chromatin. Bao X, Cai W, Deng H, Zhang W, Krencik R, Girton J, Johansen J, and Johansen KM. Journal of Biological Chemistry. 2008 November 21;283(47):32741-32750.

RNA polymerase II-mediated transcription at active loci does not require histone H3S10 phosphorylation in Drosophila. Cai W, Bao X, Deng H, Jin Y, Girton J, Johansen J, and Johansen KM. Development. 2008 September 1;135(17):2917-2925.

The JIL-1 kinase interacts with lamin Dm0 and regulates nuclear lamina morphology of Drosophila nurse cells. Bao X, Zhang W, Krencik R, Deng H, Wang Y, Girton J, Johansen J, Johansen KM. J Cell Sci. 2005 Nov 1;118(Pt 21):5079-87.

Selected Honors:

NIH/NIAMS K99/R00 Pathway to Independence Award, 2014

Albert M. Kligman Travel Fellowship Award,  2014

NIH Ruth L. Kirschstein NRSA Fellowship,  2011

Dean's Fellowship, Stanford University,  2008